| Nov 7 | Tourn | Eastern Michigan Open | — | — | Convocation Center · Ypsilanti, MI |
| Nov 13 | Non-Conf | vs. Virginia | 34–6 | 1-0 | — |
| Nov 15 | Tourn | Cyclone Open | — | — | Hilton Coliseum · Ames, IA |
| Nov 15 | Tourn | Michigan State Open | — | — | Jenison Fieldhouse · East Lansing, MI |
| Nov 15 | Tourn | Michigan State Open (Fresh/Soph) | — | — | Jenison Fieldhouse · East Lansing, MI |
| Nov 15 | Tourn | Nittany Lion Open | — | — | Bethlehem, PA |
| Nov 20 | Non-Conf | vs. Arizona State | 24–9 | 2-0 | — |
| Nov 24 | Non-Conf | @ Cleveland State | 26–12 | 3-0 | — |
| Dec 4 | Tourn | Cliff Keen Las Vegas Invitational | — | — | Las Vegas · Las Vegas, NV |
| Dec 12 | Non-Conf | @ Missouri | 17–26 | 3-1 | — |
| Dec 18 | Conf | @ Northwestern | 27–16 | 4-1 | — |
| Jan 3 | Conf | @ Illinois | 22–17 | 5-1 | — |
| Jan 9 | Conf | vs. Michigan | 11–21 | 5-2 | — |
| Jan 17 | Conf | vs. Nebraska | 21–11 | 6-2 | — |
| Jan 24 | Conf | vs. Michigan State | 33–9 | 7-2 | — |
| Jan 29 | Conf | @ Indiana | 24–12 | 8-2 | — |
| Jan 31 | Conf | @ Purdue | 20–17 | 9-2 | — |
| Feb 5 | Conf | @ Penn State | 14–24 | 9-3 | — |
| Feb 12 | Conf | vs. Wisconsin | 34–6 | 10-3 | — |
| Feb 22 | Non-Conf | vs. Edinboro | 26–13 | 11-3 | — |
| Mar 5 | Big Ten Champs | Big Ten Championships | 1263rd | — | Carver Hawkeye Arena · Iowa City, IA |
| Mar 17 | NCAA Champs | 2016 NCAA Championships | — | — | Madison Square Garden · New York, NY |
