| Nov 2 | Non-Conf | vs. Central Methodist | 43–0 | 1-0 | — |
| Nov 2 | Non-Conf | vs. Drury | 51–0 | 2-0 | — |
| Nov 2 | Non-Conf | vs. Maryville | 41–3 | 3-0 | — |
| Nov 9 | Tourn | Tiger Style Invite | — | — | Hearnes Center · Columbia, MO |
| Nov 15 | Non-Conf | @ Iowa | 3–34 | 3-1 | — |
| Nov 15 | Non-Conf | @ Michigan | 26–10 | 4-1 | — |
| Nov 15 | Non-Conf | vs. Little Rock | 34–6 | 5-1 | — |
| Nov 16 | Non-Conf | @ Illinois | 18–26 | 5-2 | — |
| Nov 16 | Non-Conf | @ Minnesota | 15–15 | 5-2-1 | — |
| Nov 24 | Non-Conf | vs. Illinois | 16–21 | 5-3-1 | — |
| Dec 5 | Non-Conf | vs. Long Island | 42–0 | 6-3-1 | — |
| Dec 5 | Non-Conf | vs. Nebraska | 10–27 | 6-4-1 | — |
| Dec 7 | Tourn | Cougar Clash | — | — | Southern Illinois University Edwardsville · Edwardsville, IL |
| Dec 14 | Conf | @ Northern Iowa | 14–22 | 6-5-1 | — |
| Dec 20 | Tourn | Kent State Holiday Classic Open | — | — | Memorial Athletic and Convocation Center · Kent, OH |
| Jan 3 | Tourn | Soldier Salute | — | — | Xtream Arena · Coralville, IA |
| Jan 15 | Conf | @ Arizona State | 22–17 | 7-5-1 | — |
| Jan 17 | Conf | @ Utah Valley | 31–9 | 8-5-1 | — |
| Jan 18 | Tourn | Cyclone Open | — | — | Hilton Coliseum · Ames, IA |
| Jan 23 | Conf | vs. Oklahoma State | 3–33 | 8-6-1 | — |
| Jan 25 | Conf | vs. Northern Colorado | 42–0 | 9-6-1 | — |
| Jan 31 | Non-Conf | @ Little Rock | 33–9 | 10-6-1 | — |
| Feb 6 | Conf | @ West Virginia | 26–13 | 11-6-1 | — |
| Feb 12 | Conf | vs. Oklahoma | 23–14 | 12-6-1 | — |
| Feb 15 | Tourn | Jackrabbits Open | — | — | Sanford Jackrabbit Athletic Complex · Brookings, SD |
| Feb 22 | Conf | @ Iowa State | 14–20 | 12-7-1 | — |
| Mar 6 | Big 12 Champs | Big 12 Championships | 84.54th | — | BOK Center · Tulsa, OK |
| Mar 19 | NCAA Champs | 2026 NCAA Championships | — | — | Rocket Arena · Cleveland, OH |
